Methylprednisolone tablets are contraindicated in patients who have: Systemic fungal infections; Known hypersensitivity to methylprednisolone tablets or to methylprednisolone, or any component of the tablet namely, lactose, monohydrate, maize starch, corn starch, liquid paraffin, sucrose, and calcium stearate.
Administration of live or live, attenuated vaccines is contraindicated in patients receiving immunosuppressive doses of corticosteroids.